Masao Fujiwara

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BACKGROUND Chemoresistance is a serious problem in pancreatic cancer, but the mechanism of resistance and strategies against the resistance have not been elucidated. We examined the potential of the phosphatidylinositol 3-kinase (PI3K)/Akt inhibitor LY294002 to enhance the anti-tumor effect of cisplatin and investigated the mechanism of chemoresistance in(More)
The upper eyelid is very difficult to reconstruct because smooth opening and closure of the eyelid must be maintained. A patient is presented in whom a hard palate mucosa-lined bipedicled myocutaneous flap containing innervated orbicularis oculi was used to successfully reconstruct a subtotal upper eyelid defect. Good functional and aesthetic results were(More)
BACKGROUND AND STUDY AIMS Small gastrointestinal stromal tumors (GISTs) rarely have malignant potential with poor prognosis. Using conventional imaging to differentiate between small GISTs and leiomyoma, which often have similar characteristics, is difficult but essential in daily practice. Although some studies have reported on the utility of serum c-kit(More)
BACKGROUND Asymptomatic diaphragmatic hernia is generally thought to be rare among adults. We present two different types of asymptomatic diaphragmatic hernia diagnosed with computed tomography (CT) and discuss treatment strategies. CASE PRESENTATION Case 1: A 37-year-old woman was diagnosed with catamenial pneumothorax in the right diaphragm. Partial(More)
The patient was a 52-year-old man who presented with right inguinal swelling and pain. He had undergone kidney transplantation in 2005 and bypass surgery using a vascular prosthesis from the left axillary artery to the bilateral femoral arteries in 2008. The vascular prosthesis had invaded the right inguinal canal ventrally. The transplanted ureter had a(More)
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