Masamitsu Kawanami

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BACKGROUND Graphene oxide (GO) is a single layer carbon sheet with a thickness of less than 1 nm. GO has good dispersibility due to surface modifications with numerous functional groups. Reduced graphene oxide (RGO) is produced via the reduction of GO, and has lower dispersibility. We examined the bioactivity of GO and RGO films, and collagen scaffolds(More)
UNLABELLED Objective : Biomodification of the root surface plays a major role in periodontal wound healing. Root surface modification with bone morphogenetic protein (BMP) stimulates bone and cementum-like tissue formation; however, severe ankylosis is simultaneously observed. Bio-safe collagen hydrogel scaffolds may therefore be useful for supplying(More)
Transiently evoked otoacoustic emission (TEOAE), distortion product otoacoustic emission (DPOAE), and spontaneous otoacoustic emission (SOAE) were measured in 45 full-term neonates (68 ears) and 12 preterm neonates (20 ears) with ILO88 & 92. Measurements were performed in the nursery of the obstetrics ward or NICU (not sound proof room) under natural(More)
According to current cochlear concepts, spontaneous otoacoustic emissions (SOAEs) are thought to be the product of outer hair cell (OHCs) movement. Furthermore, efferent neurofibers from the olivocochlear bundle primarily innervate OHCs. Thus, we designed this investigation to determine changes in SOAE under conditions of contralateral acoustic stimulation.(More)
Graphene oxide (GO) consisting of a carbon monolayer has been widely investigated for tissue engineering platforms because of its unique properties. For this study, we fabricated a GO-applied scaffold and assessed the cellular and tissue behaviors in the scaffold. A preclinical test was conducted to ascertain whether the GO scaffold promoted bone induction(More)
OBJECTIVE Collagen hydrogel scaffold exhibits bio-safe properties and facilitates periodontal wound healing. However, regenerated tissue volume is insufficient. Fibroblast growth factor-2 (FGF2) up-regulates cell behaviors and subsequent wound healing. We evaluated whether periodontal wound healing is promoted by application of collagen hydrogel scaffold in(More)
To establish clinical criteria for distortion product otoacoustic emissions (DPOAEs) in order to distinguish normal-hearing from hearing-impaired ears, DPOAEs were measured and evaluated in 325 normal and 291 cochlear-impaired human ears using an ILO92 Otoacoustic Emission Analyzer. The background noise level was too variational in each individual ear to(More)
In many studies, Evoked Otoacoustic Emissions (EOAEs) have been routinely documented in subjects with normal middle ear function showing tympanogram (TG) A type. However, middle ear dysfunction may influence the measurements of EOAEs. We investigated the EOAEs in ears with secretory otitis media (SOM) in order to understand the effects of middle ear(More)
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