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We propose a novel replacement algorithm, called Inter-Reference Gap Distribution Replacement (IGDR), for set-associative secondary caches of processors. IGDR attaches a weight to each memory-block, and on a replacement request it selects the memory-block with the smallest weight for eviction. The time difference between successive references of a(More)
Many-core architectures, such as the Intel Xeon Phi, provide dozens of cores and hundreds of hardware threads. To utilize such architectures, application programmers are increasingly looking at hybrid programming models, where multiple threads interact with the MPI library (frequently called "MPI+X" models). A common mode of operation for such applications(More)
We propose a speculative multi-threading processor architecture called Pinot. Pinot exploits parallelism over a wide range of granularities without modifying program sources. Since exploitation of fine-grain parallelism suffers from limits of parallelism and overhead incurred by parallelization, it is better to extract coarse-grain parallelism. Coarse-grain(More)
tRNA 3' processing endoribonuclease (3' tRNase) is an enzyme responsible for the removal of a 3' trailer from precursor tRNA (pre-tRNA). We purified approximately 85 kDa 3' tRNase from pig liver and determined its partial sequences. BLAST search of them suggested that the enzyme was the product of a candidate human prostate cancer susceptibility gene,(More)
The increasing prevalence of co-processors such as the Intel Xeon Phi, has been reshaping the high performance computing (HPC) landscape. The Xeon Phi comes with a large number of power efficient CPU cores, but at the same time, it's a highly memory constraint environment leaving the task of memory management entirely up to application developers. To reduce(More)
—In this paper we present " Casper, " a process-based asynchronous progress solution for MPI one-sided communication on multi-and many-core architectures. Casper uses transparent MPI call redirection through PMPI and MPI-3 shared-memory windows to map memory from multiple user processes into the address space of one or more ghost processes, thus allowing(More)
Two sets of experiments were conducted to examine the effects of two sensory modalities, temperature and taste, of foods on perceptual and motor aspects of swallowing in 20 young, healthy subjects (10 subjects for each experiment). A tasteless and odorless thickening agent was the basic testing material. The first experiment compared the swallowing of foods(More)