Masami Kato

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To investigate whether miniature pigs are useful for evaluating the potential of drugs for drug-induced prolongation of the QT interval, we performed an in vivo QT assay using conscious and unrestricted miniature pigs. Compared with the vehicle average baseline values, haloperidol at 3 and 10 mg/kg, p.o. prolonged the QTcF interval (Fridericia's formula) by(More)
The aim of this study was to assess the effect of tadalafil (0.5, 2.5, and 10 mg/kg per day) on the progression of pulmonary arterial hypertension (PAH) in early treatment and on the survival rate in late treatment on the monocrotaline (MCT)-induced PAH rat model. Tadalafil was administered once daily to rats for 3 weeks from the day of MCT-injection or 21(More)
This paper studies audio–video transmission in a wireless LAN with the EDCA of the IEEE 802.11e MAC protocol in terms of applica-tion–level QoS and user–level QoS (i.e., perceptual QoS). By simulation, we first compare the performance of the EDCA and the legacy IEEE 802.11 DCF in the case where audio, video, and data are transmitted in a common wireless(More)
— This paper examines the effect of segmenta-tion mismatch on audio-video transmission by Bluetooth. We focus on the segmentation mismatch caused by the difference between the RFCOMM Maximum Frame Size and the baseband packet payload size. By experiment, we assessed the maximum throughput and media synchronization quality for various types of ACL packets.(More)
This study evaluates the accuracy of goniometric measurement of fixated proximal interphalangeal (PIP) joints using fresh cadavers. Sixteen fingers in four right hands were evaluated. Angles of PIP joints obtained by three examiners, two methods (lateral, dorsal), three goniometers (plastic A, B, and a metal model), and four different fingers were compared(More)
A case of anthracosis of the esophagus is reported. The patient was a previously healthy 69-year-old Japanese woman. A black and slightly elevated lesion was detected in her esophagus by upper gastroesophageal fiberoscopic examination. Endoscopically, the lesion looked like malignant melanoma. Thoracic esophagotomy was then performed. Histological(More)
— This paper assesses the media synchronization quality of audio-video transmission over the IEEE 802.11b wireless LAN under Bluetooth interference by experiment. In this situation, the temporal constraints of audio and video may be disturbed, since the Bluetooth interference cause delay jitter due to retransmission and carrier sensing in the MAC layer of(More)
As a pre-processing step of image segmentation, superpixel algorithms are used to produce small, uniform and compact regions, which can be used for region-based image coding, region-based image processing, and object recognition. In order to meet the requirements of real-time applications for embedded computing, it is necessary to reduce the computational(More)