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In this paper, we propose a new method for decomposing pattern classification problems based on the class relations among training data. By using this method, we can divide a K-class classification problem into a series of ((2)(K)) two-class problems. These two-class problems are to discriminate class Ci from class Cj for i=1, ..., K and j = i+1, while the(More)
We define the degree of aperiodicity of finite automata and show that for every set M of positive integers, the class QAM of finite automata whose degree of aperiodicity belongs to the division ideal generated by M is closed with respect to direct products, disjoint unions, subautomata, homomorphic images and renamings. These closure conditions define(More)
Locomotion involves repetitive movements and is often executed unconsciously and automatically. In order to achieve smooth locomotion, the coordination of the rhythms of all physical parts is important. Neurophysiological studies have revealed that basic rhythms are produced in the spinal network called, the central pattern generator (CPG), where some(More)
The clinical efficacy of gefitinib, a tyrosine kinase inhibitor of epidermal growth factor receptor (EGFR), on brain metastases (BMs) from non-small-cell lung cancer (NSCLC) was evaluated. Fifteen patients with recurrent NSCLC with metastasis to the brain were treated with gefitinib. The objective tumor response rate (60%; 9 of 15 patients) for BM was the(More)
A b s t r a c t . In this paper, we propose a new methodology for decomposing pattern classification problems based on the class relations among training data. We also propose two combination principles for integrating individual modules to solve the original problem. By using the decomposition methodology, we can divide a K-class classification problem(More)
The distribution of Mycobacterium avium-intracellulare complex (MAC) in residences was examined. MAC was only recovered from bathrooms but not from other sites of residences. The appearance ratio in the bathrooms of patients with pulmonary MAC was significantly higher than that in healthy volunteers' bathrooms (P=.01). For 2 patients, the genotypes of(More)
BACKGROUND The tumor microenvironment, of which cancer-associated fibroblasts (CAFs) and tumor-associated macrophages (TAMs) are the major cellular components, plays an important role in tumor progression. This study evaluated the significance of podoplanin-positive CAFs and CD204-positive TAMs, which may reflect tumor-promoting CAFs and TAMs, as risk(More)
We present two cases of desmoplastic malignant mesothelioma (DMM) with pathological, immunohistochemical, and ultrastructural features. Each patient showed rapid progress and died within 1 year from appearance of the initial symptoms. Macroscopically, both showed a thickened pleura replaced by a tumor that encased the lung. Microscopic results of each(More)