Masako Nishimura

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Papillary serous carcinoma of the peritoneum (PSCP) is a primary neoplasm of peritoneal origin, and is histologically difficult to differentiate from papillary serous carcinoma of the ovary (PSCO). PSCP is frequently accompanied by many peritoneal tumors, and has been managed as a disseminated disease. In previous reports, however, the clonality of the(More)
Cholangiocarcinoma is a rare malignant disease, and recently the worldwide incidence of this malignancy has been gradually increasing. Overall, the annual incidence of cholangiocarcinoma is approximately 1.0 per 100,000 in the United States, 7.3 per 100,000 in Israel, 6.5 per 100,000 among American Indians, and 5.5 per 100,000 in Japan (1). Progress in(More)
The mechanisms responsible for oral tolerance have been analyzed using various antigens. The induction of oral nonresponsiveness to low doses of Staphylococcal Enterotoxin B (SEB), in which SEB-reactive clonal anergy and deletion are involved, has also been confirmed. However, few reports have examined the cytokine milieu of the mucosal and peripheral(More)
Biliary tract cancers (BTC) are relatively rare tumors, and the prognosis is extremely poor. There has been no standard chemotherapy for advanced BTC. However, recently, gemcitabine (GEM) have been used against BTC as the most active agent, and promising response rates and overall survival times with tolerable drug toxicities have been observed. In this(More)
Enteropathy-associated T-cell lymphoma (ETCL) is a primary extranodal T-cell lymphoma arising in the gastrointestinal tract, and is known as a rare and highly aggressive disease with a poor prognosis. The diagnosis of ETCL is usually established by histological examination using resected tumors or biopsy specimens during endoscopic studies. If tumor(More)
Gastrointe stinal stromal tumors (GISTs) constitute a category of primary nonepithe lial neoplasms of the gastrointe stinal tract, and most GISTs traditionally have been classi® ed as smooth muscle tumors (1). Malignant GIST, which is termed a le iomyosarcoma,o is the third most common neoplasm among primary malignant small bowe l tumors in Japan (2) and is(More)
Endocrine carcinomas (ECs) of the stomach reveal prominently aggressive behavior and have poor prognoses. Optimal treatments for gastric ECs have not been established because of the rarity of EC. In general, patients with gastric ECs die within a year of diagnosis in spite of surgical resections and subsequent chemotherapies. Liver metastases are the most(More)
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