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  • Masaki Shiota, Yoohyun Song, +9 authors Seiji Prof Naito
  • Biology, Medicine
  • Clinical Cancer Research
  • 2010 (First Publication: 1 December 2010)
  • Purpose: Invasion and metastasis are key steps in the progression of urothelial cancer (UC) into a critical disease. Foxo3a is a member of the Foxo transcription factor family that modulates theContinue Reading
  • Hidetoshi Kuruma, Hiroaki Matsumoto, +8 authors Amina Zoubeidi
  • Biology, Medicine
  • Molecular Cancer Therapeutics
  • 2013 (First Publication: 14 March 2013)
  • Resistance to antiandrogen drugs, like MDV3100, occurs in patients with castration-resistant prostate cancer (CRPC). Thus, preventing or treating antiandrogen resistance is a major clinicalContinue Reading
  • Masaki Shiota, Hiroto Izumi, +12 authors Kimitoshi Kohno
  • Biology, Medicine
  • Cancer research
  • 2009 (First Publication: 24 March 2009)
  • Programmed cell death protein 4 (PDCD4) has recently been shown to be involved in both transcription and translation, and to regulate cell growth. However, the mechanisms underlying PDCD4 functionContinue Reading