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Serine/arginine-rich proteins (SR proteins) constitute a family of RNA-binding proteins conserved throughout metazoans. The SR proteins are essential for constitutive pre-mRNA splicing and also affect regulated pre-mRNA splicing. We identified five putative genes encoding SR proteins (referred to as srp genes) in Caenorhabditis elegans, examined their(More)
In response to high population density or low food supply, the nematode Caenorhabditis elegans enters an alternative larval stage, known as the dauer, that can withstand adverse conditions for prolonged periods. C. elegans senses its population density through a small-molecule signal, traditionally called the dauer pheromone, that it secretes into its(More)
Tumor necrosis factor-alpha (TNF-alpha) transgenic mice have previously been found to have characteristics consistent with emphysema and severe pulmonary hypertension. Lungs demonstrated alveolar enlargement as well as interstitial thickening due to chronic inflammation and perivascular fibrosis. In the present report, we sought to determine potential(More)
We identified MRG-1, a Caenorhabditis elegans chromodomain-containing protein that is similar to the human mortality factor-related gene 15 product (MRG15). RNA-mediated interference (RNAi) of mrg-1 resulted in complete absence of the germline in both hermaphrodite and male adults. Examination of the expression of PGL-1, a component of P granules, revealed(More)
Sixteen infants were analyzed longitudinally from the onset of independent walking to 3 years of age using time parameters, speed and energy recovery. Considerable variation and irregularities were observed in many parameters of infant walking, especially until 13 months of age when infants had difficulty in walking steadily step by step. Infant walking(More)
The kinematic gait characteristics of six species of birds in three groups were compared. The groups studied were herons (Gray Herons and Little Egrets), ground-feeders (Domestic Pigeons and Gray Starlings), and waterfowl (Pintails and Black-headed Gulls). The results showed that the relative stride frequency was greater in the waterfowl than in the other(More)
Although previous studies have indicated that head bobbing of birds is an optokinetic movement, head bobbing can also be controlled by some biomechanical constraints when it occurs during walking. In the present study, the head bobbing, center of gravity, and body movements of little egrets (Egretta garzetta) during walking were examined by determination of(More)
Coordination between cell proliferation and differentiation is important in normal development and oncogenesis. These processes usually have an antagonistic relationship, in that differentiation is blocked in proliferative cells, and terminally differentiated cells do not divide. In some instances, cyclins, cyclin-dependent kinases (CDKs) and their(More)
Head-bobbing walking (HBW) and non-bobbing walking (NBW) of black-headed gulls were compared from kinematic and behavioral/environmental viewpoints. The birds walked with a longer stride length and lower stride frequency during the HBW than during the NBW. With respect to these two parameters, the HBW of black-headed gulls was similar to that of other(More)
We examined the expression of a Caenorhabditis elegans (C. elegans) elav-like gene, which we designated elr-1. The elr-1 gene encodes a predicted 456-amino-acid protein containing three putative RNA-binding domains and belongs to the ELAV family, which is functionally involved in neuronal differentiation. Northern blot analysis suggested that the levels of(More)