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Relationship between serum uric acid levels and hypertension among Japanese individuals not treated for hyperuricemia and hypertension
TLDR
Elevated serum uric acid levels may be as important as obesity, dyslipidemia, diabetes, smoking and reduced kidney function for the development of hypertension and should be considered in hypertension prevention programs. Expand
Serum alkaline phosphatase as a predictor of worsening renal function in patients with acute decompensated heart failure.
TLDR
Serum ALP is an independent predictor of WRF in the clinical course of ADHF and is associated with CKD and diabetes in patients with ADHF. Expand
Validation of the Get With The Guideline-Heart Failure risk score in Japanese patients and the potential improvement of its discrimination ability by the inclusion of B-type natriuretic peptide level.
TLDR
The Get With The Guidelines-Heart Failure risk score can be applied in Japanese AHF patients with good discrimination and calibration and could be considered in future risk models. Expand
Combined Analysis of Human and Experimental Murine Samples Identified Novel Circulating MicroRNAs as Biomarkers for Atrial Fibrillation.
TLDR
Novel circulating miRNAs were upregulated in the serum of AF patients and might be potential biomarkers of AF. Expand
Smoking, Smoking Cessation, and Measures of Subclinical Atherosclerosis in Multiple Vascular Beds in Japanese Men
TLDR
Cigarette smoking was strongly associated with subclinical atherosclerosis in multiple vascular beds in Japanese men, and these associations attenuated with time since cessation, whereas timeSince cessation among former smokers was linearly associated with lower burdens of all atherosclerotic indices. Expand
Relationship of Insulin Resistance to Prevalence and Progression of Coronary Artery Calcification Beyond Metabolic Syndrome Components: Shiga Epidemiological Study of Subclinical Atherosclerosis
TLDR
Higher IR was associated with CAC prevalence and progression independently of metabolic syndrome components in Japanese men and also in those without diabetes mellitus. Expand
Edema index measured by bioelectrical impedance analysis as a predictor of fluid reduction needed to remove clinical congestion in acute heart failure.
No abstract available Keywords: Bioelectrical impedance analysis; Congestion; Edema index; Heart failure.
In vitro generation of functional murine heart organoids via FGF4 and extracellular matrix
TLDR
This work develops a method to generate heart organoids from mouse embryonic stem cell-derived embryoid bodies that exhibit ultrastructural, histochemical and gene expression characteristics of considerable similarity to those of developmental hearts in vivo. Expand
Incidence of hospital-acquired hyponatremia by the dose and type of diuretics among patients with acute heart failure and its association with long-term outcomes.
TLDR
Thiazide diuretic use, rather than loop diuretics dose, was independently associated with HAH; and mortality was higher in thiazidediuretics users even after statistical matching. Expand
Impact of the augmentation time ratio on direct measurement of central aortic pressure in the presence of coronary artery disease
TLDR
The augmentation time ratio was an independent factor related to no CAD, especially in patients with a high augmentation index, and the augmentation Index and augmentation pressure were lower in the no CAD group, but this difference was not statistically significant. Expand
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