Masahiro Watatani

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The O 6-methylguanine-DNA methyltransferase (MGMT) protein protects cells from alkylating agents by removing alkyl groups from the O 6-position of guanine. However, its effect on DNA damage induced by cyclophospha-mide (CPM) is unclear. The present study investigated whether MGMT expression was correlated with prognosis in patients with breast cancer that(More)
Recent chemotherapies for skin metastases from breast cancer have shown to be effective for regression, disappearance, and favorable quality of life. We describe the case of a 76-year-old male showing transient effectiveness with an oral 5-fluorouracil derivative, S-1 (tegafur, 5-chloro-2,4-dihydroxypyridine and potassium oxonate), for epirubicin,(More)
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