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After a mechanical denudation of rabbit corneal endothelial cells, the healing process was followed with wide-field specular microscopy. Individual cell migration and morphologic changes were analyzed by computer-assisted morphometry. The cells surrounding the wound migrated to cover the defect without producing intercellular gaps. The greatest cellular(More)
BACKGROUND/AIMS To evaluate treatment with high peak power pulse energy by femtosecond ultrashort pulse laser (titanium sapphire laser) delivered at an 800 nm wavelength for corneal neovascularisation using photodynamic therapy (PDT) mediated by indocyanine green (ICG). METHODS Using a gelatin solid as an in vitro corneal model, the safety of laser power(More)
PURPOSE To investigate the effects of horizontal disparity on torsional optokinetic nystagmus (tOKN) in humans. METHODS Ten healthy human subjects were selected for this experiment. Monocular eye movements were recorded three-dimensionally using dual-search coil methods. Torsional OKN was induced by a rotating random-dot pattern (22 degrees in diameter,(More)
Puroose: Multiple ruptures of Bowman's membrane is a characteristic pathological finding in keratoconus corneas. We investigated to further clarify the three dimentional collagen fibrillsr architecture of keratoconus corneas and compared those with other diseased corneas. Methods: The cell maceration and conductive method were applied to the diseased(More)
The corneal endothelial permeability coefficient (Pac) for fluorescein and fluorescein glucuronide was determined in ten normal young volunteers. After oral administration of fluorescein, the apparent concentrations of both dyes in the corneal stroma and the anterior chamber were measured by differential fluorometry. The apparent dye levels calculated(More)
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