Masahiro Kobayashi

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Recently, encouraging AIDS vaccine trials in macaques have implicated cytotoxic T lymphocytes (CTLs) in the control of the simian human immunodeficiency virus SHIV89.6P that induces acute CD4(+) T cell depletion. However, none of these vaccine regimens have been successful in the containment of replication of the pathogenic simian immunodeficiency viruses(More)
Nori, a marine red alga, is one of the most profitable mariculture crops in the world. However, the biological properties of this macroalga are poorly understood at the molecular level. In this study, we determined the draft genome sequence of susabi-nori (Pyropia yezoensis) using next-generation sequencing platforms. For sequencing, thalli of P. yezoensis(More)
—During the last several years, the Internet has evolved from a wired infrastructure to a hybrid of wired and wireless domains by spreading worldwide interoperability for microwave access (WiMAX), Wi-Fi, and cellular networks. Therefore, there is a growing need to facilitate reliable content delivery over such heterogeneous networks. On the other hand,(More)
  • Kensuke Kojima, Craig April, Claudia Canasto-Chibuque, Xintong Chen, Manjeet Deshmukh, Anu Venkatesh +5 others
  • 2014
BACKGROUND Archived tissues from previously completed prospective trials represent invaluable resource for biomarker development. However, such specimens are often stored as sections on glass slides, in which RNA is severely degraded due to prolonged air exposure. We evaluated whether a proportion of archived sectioned formalin-fixed paraffin-embedded(More)
In this paper we present the specification and the structure of EDR Electronic Dictionary which was developed in a nine-year project. The first version of EDR dictionary (V1.0) and its revised version (V1.5) are "already released and are now utilized at many sites for both academic and commercial purposes. We also describe the current status how the EDR(More)
EZH2, a core component of polycomb repressive complex 2 (PRC2), plays a role in transcriptional repression through histone H3 Lys-27 trimethylation and is involved in various biological processes, including hematopoiesis. It is well known that 3-deazaneplanocin A (DZNep), an inhibitor of S-adenosylmethionine-dependent methyltransferase that targets the(More)
Miriplatin is a novel lipophilic platinum complex that was developed to treat hepatocellular carcinoma (HCC). Although HCC patients frequently have coexisting chronic renal failure, little prospective data are available regarding the clinical toxicity of chemotherapeutic agents used to treat HCC patients with chronic renal failure. In a phase II study, the(More)