Masahiro Kobayashi

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Nori, a marine red alga, is one of the most profitable mariculture crops in the world. However, the biological properties of this macroalga are poorly understood at the molecular level. In this study, we determined the draft genome sequence of susabi-nori (Pyropia yezoensis) using next-generation sequencing platforms. For sequencing, thalli of P. yezoensis(More)
Recently, encouraging AIDS vaccine trials in macaques have implicated cytotoxic T lymphocytes (CTLs) in the control of the simian human immunodeficiency virus SHIV89.6P that induces acute CD4(+) T cell depletion. However, none of these vaccine regimens have been successful in the containment of replication of the pathogenic simian immunodeficiency viruses(More)
—During the last several years, the Internet has evolved from a wired infrastructure to a hybrid of wired and wireless domains by spreading worldwide interoperability for microwave access (WiMAX), Wi-Fi, and cellular networks. Therefore, there is a growing need to facilitate reliable content delivery over such heterogeneous networks. On the other hand,(More)
In this paper we present the specification and the structure of EDR Electronic Dictionary which was developed in a nine-year project. The first version of EDR dictionary (V1.0) and its revised version (V1.5) are "already released and are now utilized at many sites for both academic and commercial purposes. We also describe the current status how the EDR(More)
BACKGROUND Archived tissues from previously completed prospective trials represent invaluable resource for biomarker development. However, such specimens are often stored as sections on glass slides, in which RNA is severely degraded due to prolonged air exposure. We evaluated whether a proportion of archived sectioned formalin-fixed paraffin-embedded(More)
EZH2, a core component of polycomb repressive complex 2 (PRC2), plays a role in transcriptional repression through histone H3 Lys-27 trimethylation and is involved in various biological processes, including hematopoiesis. It is well known that 3-deazaneplanocin A (DZNep), an inhibitor of S-adenosylmethionine-dependent methyltransferase that targets the(More)
  • Alessandro Sciamarelli, Katalin Dobranszky-Bartus, Frans Meel, Jindrich Thon, Jonas Grincius, Marja Elsinga +7 others
  • 2011
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Ectopic lymphoid-like structures (ELSs) are often observed in cancer, yet their function is obscure. Although ELSs signify good prognosis in certain malignancies, we found that hepatic ELSs indicated poor prognosis for hepatocellular carcinoma (HCC). We studied an HCC mouse model that displayed abundant ELSs and found that they constituted(More)