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Recent studies show that dendritic spines are dynamic structures. Their rapid creation, destruction and shape-changing are essential for short- and long-term plasticity at excitatory synapses on pyramidal neurons in the cerebral cortex. The onset of long-term potentiation, spine-volume growth and an increase in receptor trafficking are coincident, enabling… (More)
NarK belongs to the nitrate/nitrite porter (NNP) family in the major facilitator superfamily (MFS) and plays a central role in nitrate uptake across the membrane in diverse organisms, including archaea, bacteria, fungi and plants. Although previous studies provided insight into the overall structure and the substrate recognition of NarK, its molecular… (More)
Global warming effects on seaweed beds are already perceptible. Their geographical distributions greatly depend on water temperatures. To predict future geographical distributions of brown alga, Sargassum horneri, forming large beds in the northwestern Pacific, we referred to future monthly surface water temperatures at about 1.1° of longitude and 0.6° of… (More)
The NWT was reinforced to get 280 GFLOPS of theoretical peak performance with the addition of 26 PEs to the original 140 PEs. On a CFD simulation of jet engine compressor, we attained active performance speed of 111 GFLOPS using 160 PEs.
NAL Numerical Wind Tunnel (NWT) is a distributed memory parallel computer developed through joint research and development of NAL and Fujitsu. It is based on the analysis of CFD codes developed in NAL. The target performance is more than 100 times faster than VP400.In this paper, the parallel computation model employed in the development of the NWT is… (More)
A portable QCD simulation program running on NWT with 128 PE's shows the performance 0.032 micro sec/link update, which is about 189 times faster than a highly optimized code on CRAY X-MP/48 with four processors. The performance corresponds to 178 GFLOPS sustained speed.
To represent both the basin-scale circulation in the ocean and the local small-scale variations at the same time, a high resolution global ocean general circulation model (OGCM) is essential. Recent progress in parallel computing techniques together with the high ability of computer itself makes it possible to use such a high resolution OGCM for climate… (More)
Bacteriorhodopsin (bR) is a light-driven proton pump and a model membrane transport protein. We used time-resolved serial femtosecond crystallography at an x-ray free electron laser to visualize conformational changes in bR from nanoseconds to milliseconds following photoactivation. An initially twisted retinal chromophore displaces a conserved tryptophan… (More)