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Effects of a bradykinin B(2) receptor antagonist on ischemia-reperfusion injury in a canine lung transplantation model.
BACKGROUND This study investigated the effects of a bradykinin B(2) receptor antagonist, FR173657 (FR), on ischemia-reperfusion (I/R) injury in a canine lung transplantation model. METHODS EighteenExpand
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Effects of FK3311 on pulmonary ischemia-reperfusion injury in a canine model.
BACKGROUND This study investigated the effects of a selective COX-2 inhibitor, FK3311, on warm ischemia-reperfusion (I/R) injury in the canine lung. MATERIALS AND METHODS Sixteen adult mongrel dogsExpand
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Effects of a p38 mitogen-activated protein kinase inhibitor as an additive to Euro-Collins solution on reperfusion injury in canine lung transplantation1
Background. The activation of p38 mitogen-activated protein kinase (MAPK) plays an important role in the development of ischemia/reperfusion injury. FR167653 is a novel p38 MAPK inhibitor. This studyExpand
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Effects of a bradykinin B(2) receptor antagonist, FR173657, on pulmonary ischemia-reperfusion injury in dogs.
BACKGROUND This study investigated the effects of a bradykinin B(2) receptor antagonist, FR173657 (FR), on pulmonary ischemia-reperfusion (I/R) injury. METHODS Twenty-four mongrel dogs were dividedExpand
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Cardiac transplantation following a 24-h preservation using a perfusion apparatus.
BACKGROUND We developed a new apparatus for heart preservation and have already reported successful transplantation following 12 h of preservation using this apparatus. The efficacy of coronaryExpand
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Effects of adding P38 mitogen-activated protein-kinase inhibitor to celsior solution in canine heart transplantation from non–heart-beating donors
Background. The activation of p38 mitogen-activated protein kinase (MAPK) plays an important role in ischemia-reperfusion injury. This study evaluated the effects of p38 MAPK inhibition usingExpand
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The optimal pressure for initial flush with UW solution in heart procurement.
OBJECTIVE University of Wisconsin (UW) solution is widely used in organ preservation. Some investigators have reported that high pressure during initial flush with UW solution may induceExpand
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The effects of a bradykinin B2 receptor antagonist in extended liver resection with ischemia in dogs.
BACKGROUND/AIMS In liver surgery, total clamping of the portal triad (Pringle's procedure) is commonly used, and sometimes causes liver failure. This study evaluated the effects of a bradykinin B2Expand
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The optimal pressure for initial flushout in heart procurement with the UW solution.
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