Masahiko Taguchi

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Immune cell migration into and through mucosal barrier sites in general and airway sites in particular is a critical feature of immune and inflammatory responses, but the determinants of transepithelial (unlike transendothelial) immune cell traffic are poorly defined. Accordingly, we used primary culture airway epithelial cells and peripheral blood(More)
A minute small-cell lung cancer measuring 8 x 5 mm was detected and serially imaged by computed tomography for about a year preceding resection. Although this solid nodule showed a short overall doubling time (76 days), the growth curve included an early phase without apparent growth prior to the phase of rapid growth. Accordingly, lung cancer cannot be(More)
BACKGROUND Prognostic implications of overexpression of the HER-2 gene in nonsmall cell lung carcinoma (NSCLC) are a matter of controversy. Many conflicting results have been reported from different laboratories. METHODS A metaanalysis of published studies was performed for this quantitative review of the effects of HER-2 overexpression on survival among(More)
PURPOSE Fluorodeoxyglucose positron emission tomography integrated with computed tomography (FDGPET/CT) was evaluated as a routine staging technique for primary lung cancer. MATERIALS AND METHODS We prospectively compared FDG-PET/CT in determining clinical stage and surgical indication with conventional staging not including positron emission tomography(More)
STUDY OBJECTIVE The aim of this study was to clarify whether fluorescence in situ hybridization (FISH) can diagnose lung cancer in various clinical specimens in comparison with conventional cytology. DESIGN Prospective study. SETTING University hospital in a metropolitan area. PATIENTS Fifty consecutive patients with abnormal chest radiography or CT(More)
A 74-year-old man presented to our hospital with persistent low-grade back pain that had continued for 6 months. An expansile tumor containing delicate bony trabeculae was found in the posterior portion of the left fifth rib. Preoperative examination of a percutaneous needle biopsy specimen suggested a diagnosis of hemangioma; postoperative pathology(More)
The efficacy of preoperative chemotherapy for improving postoperative survival in patients with non-small-cell lung cancer (NSCLC) is controversial. We therefore conducted a meta-analysis of the published phase III randomized clinical trials (RCTs) to quantitatively evaluate the survival benefit of preoperative chemotherapy. After searching the MEDLINE(More)
BACKGROUND We report a new method for collecting and establishing small airway epithelial cells (SAEC). This method enables the evaluation of the cytokine responsiveness of SAEC, which is still unknown. In this study we evaluated intercellular adhesion molecule-1 (ICAM-1) expression on SAEC stimulated with several inflammatory cytokines and compared it with(More)
MOSFET harmonic distortion characteristics up to the cutoff frequency (f<sub>T</sub>) are measured and analyzed with the MOSFET model HiSIM. While distortion characteristics at low frequency are determined by carrier mobility, characteristics at high frequency are influenced by the time delay of carriers to form the channel. At low frequency, IP3 values,(More)
A retrospective study of limited resection for lung cancer in a large number of patients was first reported in the 1970s. The reported outcome of segmentectomy was comparable to that of standard lobectomy. The North American Lung Cancer Study Group (LCSG) performed a randomized controlled clinical trial to compare limited resection (segment or wedge) with(More)