Masahiko Saito

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INTRODUCTION Nerve growth factor (NGF) has an important role in the generation of discogenic pain. We hypothesized that annular rupture is a trigger for discogenic pain through the action of NGF. In this study, the protein levels of NGF in discs from patients with disc herniation were examined and compared with those from discs of patients with other lumbar(More)
  • Shimizu S, Higashi Y, +5 authors M Saito
  • 2015
Hypothesis/aims of study Psychological stress exacerbates symptoms of urinary bladder dysfunction including overactive bladder and painful bladder syndrome, but the underlying mechanisms are unknown. Bombesin (BB)-related peptides have been implicated in the mediation/integration of stress responses through brain BB receptors [1]. Actually, in rodent(More)
BACKGROUND The importance of pelvic incidence-lumbar lordosis (PI-LL: PI minus LL) mismatch is emphasized in long-segment fusion for adult spinal deformity; however, there are few studies evaluating the influence of PI-LL on surgical outcomes after short-segment fusion. In this study, we have examined the effects of PI-LL mismatch on surgical outcomes of(More)
It is known that the severity of compression myelopathy sometimes worsens rapidly and results in poor functional recovery because of limited axonal regeneration. Levels of phosphorylated neurofilament subunit NF-H (pNF-H), which indicate axonal degeneration, are elevated in other neurological disorders. To our knowledge, there has been no examination of(More)
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