Masaaki Shimizu

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BACKGROUND Enumeration of chemical graphs satisfying given constraints is one of the fundamental problems in chemoinformatics and bioinformatics since it leads to a variety of useful applications including structure determination of novel chemical compounds and drug design. RESULTS In this paper, we consider the problem of enumerating all tree-like(More)
We have been developing a large scale PC cluster named PACS-CS (Parallel Array Computer System for Computational Sciences) at Center for Computational Sciences, University of Tsukuba, for wide variety of computational science applications such as computational physics, computational material science, computational biology, etc. We consider the most(More)
The patient was a 52-year-old woman. She had been aware of her bilateral hearing loss since she was 20 years old. The hearing in her left ear started to deteriorate at the age of 49. Pure-tone audiometry showed a bilateral mixed hearing loss. The hearing levels for the right ear and the left ear were 52 dB and 68 dB, respectively. There were no remarkable(More)
We have examined a tonal system of modern Hanoi dialect of Vietnamese. This has been described for a long time as a pitch contour prominent system with secondary phonatory variations. The present study aims to propose certain laryngeal features, [tense] and [glottal constriction], in addition to the former prosodic feature, [high], to cover the overall(More)
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