Masaaki Iwahashi

Learn More
The distribution of the extracellular matrix, including type I, III, IV and VI collagens and laminin, and of prolyl hydroxylase was investigated in the human endometrium by an indirect immunofluorescence method with specific monoclonal antibodies. Collagens were also extracted from the endometrial tissues in the proliferative and secretory phases and from(More)
PURPOSE The effect of local injection of anticancer drugs by balloon catheter, i.e., balloon occluded arterial infusion (BOAI), on the prognosis of cervical cancer treated with radiotherapy were retrospectively estimated. METHODS AND MATERIALS Sixty-five patients with cervical cancer (Stage I-IV) treated by irradiation were included in the study. Among(More)
OBJECTIVE To identify type VI collagen expression in human ovarian follicles during follicular growth. DESIGN In vitro experiment. SETTING Department of Obstetrics and Gynecology, Wakayama Medical College, Japan. PATIENT(S) Regularly cycling women who underwent adnexectomy. INTERVENTION(S) Immunohistochemistry and in situ hybridization for human(More)
OBJECTIVE To investigate the characteristic structure and function of human corpora lutea (CL), various types of collagen expression were determined in the CL tissues during the menstrual cycle and early pregnancy. DESIGN In vitro experiment. SETTING Department of obstetrics and gynecology at a medical university. PATIENT(S) Regulatory cycling women(More)
To provide some insight into the etiology of spontaneous abortion, the expression of type IV collagen was investigated in human decidual tissues obtained after spontaneous abortion (n = 17) and normal pregnancy (n = 22). Indirect immunofluorescent staining was performed for type I, III, and IV collagen as well as laminin, and Northern blot analysis was(More)
To provide some insight into the mechanism of cervical ripening, the expression of type I collagen was investigated in human uterine cervical tissues obtained from the first (n = 4) and third (n = 3) trimesters of normal pregnancy. Indirect immunofluorescent staining was performed for type I collagen, and Northern blot analysis was done to assess expression(More)
Sodium dodecyl sulfate-polyacrylamide gel electrophoresis analysis showed that the ratios of type I and type V collagen expression were significantly increased in the leiomyoma tissues at the protein level, as compared with those in the normal myometrium tissues through the menstrual cycle. These results suggest that increased expression of type I and type(More)
OBJECTIVE To investigate the possible involvement of collagen in the characteristic structure and function of human corpora lutea (CL), type V collagen expression was determined in the CL tissues during the menstrual cycle and early pregnancy. DESIGN In vitro experiment. SETTING Department of Obstetrics and Gynecology, Wakayama Medical University,(More)
A 65 year old woman presented with an ovarian mass. Ultrasonography and computed tomography findings, and an increased serum oestrogen concentration were suggestive of an oestrogen producing ovarian tumour. The tumour was removed surgically and weighed 460 g. The pathological diagnosis was adult-type granulosa cell tumour. Strong immunohistochemical(More)
AIM To provide some insight into the aetiology of spontaneous abortion, the contents of type V collagen was investigated in human decidual tissues in spontaneous abortion and normal pregnancy. METHODS Collagens were extracted from decidual tissues in spontaneous abortion (n = 19) and normal pregnancy (n = 25). The different types of collagen alpha chains(More)