Marzia Di Filippo

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The metabolic rearrangements occurring in cancer cells can be effectively investigated with a Systems Biology approach supported by metabolic network modeling. We here present tissue-specific constraint-based core models for three different types of tumors (liver, breast and lung) that serve this purpose. The core models were extracted and manually curated(More)
The intratumor heterogeneity has been recognized to characterize cancer cells impairing the efficacy of cancer treatments. We here propose an extension of constraint-based modeling approach in order to simulate metabolism of cell populations with the aim to provide a more complete characterization of these systems, especially focusing on the relationships(More)
Inverter-fed Induction motor performance is known to be noticeably affected by the supply voltage waveform. Nevertheless, the prediction of how supply voltage harmonics impact on motor operation in terms of losses, noise and thermal behavior is still a problem that can be hardly approached through simulations and analysis, therefore experimental data(More)
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