Marzeyeh Tavalaee

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OBJECTIVE To evaluate the influence of DNA fragmentation, DNA methylation, and protamine deficiency as indicators of chromatin status on assisted reproductive technology outcome, and also to assess the relation between these parameters. DESIGN Prospective study. SETTING Royan Institute and Isfahan Fertility and Infertility Center. PATIENT(S) Semen(More)
OBJECTIVE To evaluate the relationship between late spermiogenic events, including histone-protamine replacement, acrosome integrity, and sperm morphology, with fertilization rate after intracytoplasmic sperm injection (ICSI). DESIGN Prospective study. SETTING Isfahan Fertility and Infertility Center, Royan Institute, Tehran, Iran. PATIENT(S) Semen(More)
OBJECTIVE To evaluate efficiency of ionomycin on fertilization and cleavage rates, embryo development, and pregnancy rate after intracytoplasmic sperm injection (ICSI) in teratozoospermic patients. DESIGN Laboratory study. SETTING Isfahan fertility and infertility Center, and Royan institute, Tehran, Iran. PATIENT(S) Eighty-seven couples with male(More)
The aim of this study was to assess the potential of dihydrorhodamine 123 (DHR123) to measure oxidative stress produced by human spermatozoa. The results were compared with 2', 7'-dichlorodihydrofluorescein diacetate (DCFH-DA) that is routinely used for assessment of H(2)O(2) produced by spermatozoa. Fluorescence intensity and percentage R123 and DCF(More)
The aim of this study was to determine if there are any associations between impaired chromatin packaging and the origin of reactive oxygen species (ROS) production. Cytosolic ROS, mitochondrial ROS, DNA protamination, and apoptosis were evaluated with dichlorofluoresceindiacetate (DCFH-DA), dihydrorhodamine 123 (DHR123), chromomycin A3 (CMA3), and YO-Pro-1(More)
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