Maryann MacNeil

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This review compares the behavioral, physiological and anatomical repercussions of lesions of primary visual cortex incurred by developing and mature humans, monkey and cats. Comparison of the data on the repercussions following lesions incurred earlier or later in life suggests that earlier, but not later, damage unmasks a latent flexibility of the brain(More)
The purpose of the present study was to identify expansions in thalamic projections to middle suprasylvian (MS) cortex that could be linked to the sparing of visually guided behaviors that follow the removal of visual cortex early in postnatal life. Injections of retrograde tracers were made into the medial bank of the middle suprasylvian sulcus in intact,(More)
Traumatic brain injury poses significant and diverse challenges to rehabilitation efforts. Neurobehavioural deficits represent a particularly difficult barrier to rehabilitative progress and societal reintegration. Early studies have identified dopaminergic drugs such as amantadine, bromocriptine and sinemet as potentially assistive in countering these(More)
Extrastriate visual areas on the banks of the middle suprasylvian sulcus were inactivated by cooling to assess the behavioral contribution of this cortical region to the extraction of a stationary figure from a moving mask. Cooling blocked figure-ground separation when the mask was moving but had no influence when the mask was static. This difference(More)
We investigated the constancy and variability in the numbers of thalamic and cortical neurons projecting to cat middle suprasylvian (MS) visual cortex. Retrograde pathway tracers were injected at a single anatomically and physiologically defined locus in MS cortex. Counts of labeled neurons showed that the visual thalamic projections to MS cortex(More)
Retrograde tracers were injected into middle suprasylvian (MS) cortex of two groups of experimental adult cats that had incurred removal of visual areas 17 and 18 on either the day of birth (P1), or at 1 month of age (P28). Tracers were also injected into the same region of intact and adult ablated control cats. The locations and numbers of labeled neurons(More)
Removal of cat areas 17 and 18 early, but not late, in postnatal development results in the sparing of certain reflexive and nonreflexive visually guided behaviors. These spared behaviors are accompanied by an expansion of geniculocortical projections to middle suprasylvian (MS) cortex. However, little is known about the types of visual signals relayed(More)
Contemporary equipment used for nerve conduction studies is usually capable of computerized measurement of latency, amplitude, duration, and area of nerve and muscle action potentials and resulting conduction velocities. Abnormalities can be due to technical error or disease. Identification of technical error is a major element of quality control in(More)
In an effort to investigate the possibility of noncholinergic nicotine sites within the brain, psychopharmacological, biochemical and eletrophysiological studies were undertaken with nicotine and various newly synthesized derivatives of nicotine and piperidine. When 1-10 micrograms of (-)-nicotine was injected into the region of the lateral ventricle of(More)
Receiver operating characteristic (ROC) curves were used to predict the risk of carpal tunnel syndrome (CTS). Patients were classified clinically as: (1) normal exam and no symptoms (169 hands); (2) having a motor and/or sensory deficit typical of CTS (115 hands); (3) having a history characteristic of CTS (156 hands); and (4) nondiagnostic symptomatology(More)