MaryBeth Bruch

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Sentinel lymph node (SLN) metastasis is the first step in the spreading of cancer in many malignancies. Tumor-reactive lymphadenopathy in SLNs has been observed for decades, but alterations of the lymphatic channels and vasculature in these nodes before the arrival of metastatic tumor cells remain unexplored. Using animal models, we show here that, before(More)
BACKGROUND Gamma-glutamyltransferase (GGT) - a membrane-bound enzyme crucially involved in the cell's detoxification pathway and apoptotic balance - is involved in tumour development, progression and chemotherapy resistance. Elevated GGT serum levels are associated with increased cancer risk in women and worse prognosis in gynaecologic cancers. The present(More)
Of 64 patients, who had undergone operation because of a carpal tunnel syndrome in the years 1982 to 1984, 39 patients could be reinvestigated. The measurement of the distal motor latency was useful as well in the diagnosis as in the course of the CTS. After operation the distal motor latency was normal in about 70.7% of the cases. A subjective improvement(More)
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