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§ 1. Preliminary Considerations. 1. Many applications of mathematics have been made to biology. In the first place come the researches on physiological questions relative to the senses, to the circulation of the blood, to the movement of animals, which can be viewed as subjects of optics, of acoustics, of hydrodynamics or of the mechanics of solid bodies(More)
BACKGROUND A number of single case reports have suggested that the context within which intervention studies take place may challenge the assumptions that underpin randomised controlled trials (RCTs). However, the diverse ways in which context may challenge the central tenets of the RCT, and the degree to which this information is known to researchers or(More)
BACKGROUND This study aimed to systematically review and synthesise qualitative studies of employment and cancer. METHODS A rigorous systematic review and meta-synthesis process was followed. A total of 13,233 papers were retrieved from eight databases; 69 were deemed relevant following title and abstract appraisal. Four further publications were(More)
BACKGROUND AND PURPOSE Evidence on which to base decisions about the management of radiation skin reactions is lacking. The purpose of this study was to investigate whether sucralfate or aqueous cream reduced acute skin toxicity during radiotherapy to the head and neck, breast or anorectal area (phase A), and to evaluate the effect of hydrogels and dry(More)
OBJECTIVE To assess the effectiveness of nurse led follow up in the management of patients with lung cancer. DESIGN Randomised controlled trial. SETTING Specialist cancer hospital and three cancer units in southeastern England. PARTICIPANTS 203 patients with lung cancer who had completed their initial treatment and were expected to survive for at(More)
OBJECTIVE To summarise patients' experiences of head and neck cancer (HNC) by examining the findings of existing qualitative studies METHODS We undertook a systematic review and meta-synthesis of qualitative studies in 29 published articles using Noblit and Hare's 'meta-ethnography' approach to synthesise findings. The inclusion criteria were primary(More)
Aim: The primary objective of the survey was to evaluate clinical skin care practice in radiotherapy departments across the United Kingdom. Methods and Sample: A questionnaire containing sixty-one questions grouped into eight themed sections was developed and a link to an on-line survey, using the Survey Monkey tool, was e-mailed to all radiotherapy(More)
The purpose of this study was to test a brief orientation program for reducing anxiety, depressive symptoms, and overall distress in cancer patients at their initial clinic visit. One hundred and fifty consecutively referred patients seen in an oncology outpatient clinic were randomly assigned to an intervention or usual care control group. The intervention(More)
AIMS AND OBJECTIVES To evaluate a nurse-led clinic for patients undergoing radiotherapy to the head and neck. BACKGROUND The side effects of radiotherapy to the head and neck are superimposed on already significant physical and psychological morbidity. Medical review clinics tend to focus on treatment complications and there is evidence that specialist(More)
The acceptability and feasibility of a 3-month personalised lifestyle (diet, exercise and weight management) intervention in overweight adults who had completed curative treatment for colorectal cancer were assessed by qualitative interviews, quality-of-life questionnaires and subjective and objective measures of diet and activity. Over a 4-month period, 28(More)