Learn More
Theory predicts widespread loss of genetic diversity from drift and inbreeding in trees subjected to habitat fragmentation, yet empirical support of this theory is scarce. We argue that population genetics theory may be misapplied in light of ecological realities that, when recognized, require scrutiny of underlying evolutionary assumptions. One ecological(More)
Reconstruction of sibling relationships from genetic data is an important component of many biological applications. In particular, the growing application of molecular markers (microsatellites) to study wild populations of plant and animals has created the need for new computational methods of establishing pedigree relationships, such as sibgroups, among(More)
I do not believe that the accident of birth makes people sisters and brothers. It makes them sib-lings. Gives them mutuality of parentage. Abstract New technologies for collecting genotypic data from natural populations open the possibilities of investigating many fundamental biological phenomena, including behavior , mating systems, heritabilities of(More)
Reconstructions of the human-African great ape phylogeny by using mitochondrial DNA (mtDNA) have been subject to considerable debate. One confounding factor may be the lack of data on intraspecific variation. To test this hypothesis, we examined the effect of intraspecific mtDNA diversity on the phylogenetic reconstruction of another Plio-Pleistocene(More)
Kinship analysis using genetic data is important for many biological applications, including many in conservation biology. Wide availability of microsatellites has boosted studies in wild populations that rely on the knowledge of kinship, particularly sibling relationships (sibship). While there exist many methods for reconstructing sibling relationships,(More)
We present a new algorithm for reconstructing sib-ling relationships in a single generation of individuals without parental information, using data from codominant DNA markers such as microsatellites. We use the simple genetic constraints on the full-sibling groups, imposed by the Mendelian inheritance rules, and combinatorial optimization techniques to(More)
A new combinatorial approach for modeling and reconstructing sibling relationships in a single generation of individuals without parental information is proposed in this paper. Simple genetic constraints on the full-sibling groups, imposed by the Mendelian inheritance rules, are employed to investigate data from codominant DNA markers. To extract the(More)
A software suite KINALYZER reconstructs full-sibling groups without parental information using data from codominant marker loci such as microsatellites. KINALYZER utilizes a new algorithm for sibling reconstruction in diploid organisms based on combinatorial optimization. KINALYZER makes use of a Minimum 2-Allele Set Cover approach based on Mendelian(More)
With improved tools for collecting genetic data from natural and experimental populations, new opportunities arise to study fundamental biological processes, including behavior, mating systems, adaptive trait evolution, and dispersal patterns. Full use of the newly available genetic data often depends upon reconstructing genealogical relationships of(More)