Mary T Killackey

Learn More
Interstitial pneumonia in a transplant patient can have a varied etiology. Sirolimus (Rapamycin; Rapamune) is a popularly used immunosuppressant in solid organ transplantation that has anecdotally been associated with pulmonary toxicity. Sirolimus-induced pulmonary toxicity consists of a range of syndromes that is characterized by the presence of organizing(More)
BACKGROUND Cytomegalovirus (CMV) disease is a serious infection after kidney transplantation. The risk factors and the impact of CMV disease in African-American (AA) kidney transplant patients have not been well characterized. METHODS We performed a retrospective analysis on 448 AA patients transplanted between 1996 and 2005. A 3-month universal(More)
BACKGROUND Because of a critical shortage of deceased donor (DD) livers, more extended criteria allografts are being utilized; these allografts are at increased risk for ischemia-reperfusion injury (IRI). We assessed whether, in a large cohort of patients transplanted for hepatitis C virus (HCV) either via a DD or live donor (LD), there was a relationship(More)
BACKGROUND Living donor kidneys with multiple arteries (MA) are increasingly procured laparoscopically for transplant. METHODS We compare long-term graft function and survival of kidneys with single arteries (SA) and MA over a 10-year period. RESULTS There were a total of 218 grafts with SA and 60 grafts with MA. The MA group had longer operative and(More)
Hepatocellular carcinoma with extension into the right heart is a recognized, albeit rare occurrence. Patients who present with tumors extending into the heart have generally been considered inoperable and had limited survival, many sustaining tumor embolism and/or sudden death. Resection has been fraught with intraoperative and perioperative mortality as(More)
INTRODUCTION We examined the effects of increasing human leukocyte antigen (HLA) mismatches (MM) on long-term graft outcomes in patients transplanted with a panel reactive antibody (PRA) >80% over a 10-yr period. METHODS A total of 142 recipients were divided into three groups based on the number of HLA MM with their allograft (0-2, 3-4 and 5-6 MM; Groups(More)
FSGS recurs in approximately 30% of transplanted kidneys and may lead to graft loss. We retrospectively examined the efficacy of early and intensive PP without additional IS in pediatric kidney transplant patients with recurrent FSGS at our center. Seven of 24 patients (29%) had nephrotic proteinuria and histologic evidence of FSGS recurrence within 1-5(More)
BACKGROUND The purpose of this study was to determine the incidence and management strategies for post-transplant leukopenia/neutropenia in kidney recipients receiving alemtuzumab induction during the first year following transplantation. METHODS We prospectively identified 233 adult patients who underwent kidney transplantation with alemtuzumab induction(More)
Undertaking transplantation in highly sensitized African American (AA) patients as transplant recipients represents a unique challenge. We retrospectively compared the outcomes of AA with non-African American (NAA) patients who had panel reactive antibody >80% and received deceased donor (DD) kidneys by virtual crossmatch. Immunosuppressive regimen included(More)
Organ transplantation between identical twins is a relatively rare event that has been performed for kidney, pancreas, small bowel, and liver transplants. Monozygotic twins have identical HLA genes that enable the theoretical opportunity of avoiding immunosuppressant medications following transplantation; and with it, the often-serious side effects and(More)