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INTRODUCTION Type 1 diabetes (T1D) in children and adolescents is increasing worldwide with a particular increase in children <5 years. Fewer than 1 in 6 children and adolescents achieve recommended glycated hemoglobin (HbA1c) values. METHODS A pragmatic, cluster-randomized controlled trial assessed the efficacy of a clinic-based structured educational(More)
OBJECTIVE To evaluate the effectiveness of youth development in reducing teenage pregnancy, substance use, and other outcomes. DESIGN Prospective matched comparison study. SETTING 54 youth service sites in England. PARTICIPANTS Young people (n=2724) aged 13-15 years at baseline deemed by professionals as at risk of teenage pregnancy, substance misuse,(More)
BACKGROUND There is recognition of an urgent need for clinic-based interventions for young people with type 1 diabetes mellitus that improve glycemic control and quality of life. The Child and Adolescent Structured Competencies Approach to Diabetes Education (CASCADE) is a structured educational group program, using psychological techniques, delivered(More)
The nuts and bolts of conducting an integrated process evaluation: a presentation on the role and methods of the process evaluation integrated into a trial of a complex educational intervention for young people with diabetes (CASCADE) The CASCADE study was a pragmatic cluster RCT, with integral process and economic evaluations, of a complex(More)
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