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INTRODUCTION Type 1 diabetes (T1D) in children and adolescents is increasing worldwide with a particular increase in children <5 years. Fewer than 1 in 6 children and adolescents achieve recommended glycated hemoglobin (HbA1c) values. METHODS A pragmatic, cluster-randomized controlled trial assessed the efficacy of a clinic-based structured educational(More)
As part of a larger study designed to improve doctor-patient communication in randomised clinical trials (RCT), we audiotaped the discussions between doctor and patient in which consent was being obtained for a RCT. This paper reports on 82 discussions conducted by 5 clinical oncologists in both District General and University Hospital outpatient(More)
OBJECTIVE To evaluate the effectiveness of youth development in reducing teenage pregnancy, substance use, and other outcomes. DESIGN Prospective matched comparison study. SETTING 54 youth service sites in England. PARTICIPANTS Young people (n=2724) aged 13-15 years at baseline deemed by professionals as at risk of teenage pregnancy, substance misuse,(More)
BACKGROUND Type 1 diabetes (T1D) in children and young people is increasing worldwide with a particular increase in children under the age of 5 years. Fewer than one in six children and young people achieve glycosylated fraction of haemoglobin (HbA1c) values in the range identified as providing best future outcomes. There is an urgent need for clinic-based(More)
The aim of this study was to test an instrument which might be useful for doctors in explaining the randomisation procedure to an individual patient. The sample comprised 323 patients with cancer attending for out-patient appointments and/or chemotherapy treatment in two major cancer centres in the U.K. 315 patients completed a self-report(More)
BACKGROUND There is recognition of an urgent need for clinic-based interventions for young people with type 1 diabetes mellitus that improve glycemic control and quality of life. The Child and Adolescent Structured Competencies Approach to Diabetes Education (CASCADE) is a structured educational group program, using psychological techniques, delivered(More)
The nuts and bolts of conducting an integrated process evaluation: a presentation on the role and methods of the process evaluation integrated into a trial of a complex educational intervention for young people with diabetes (CASCADE) The CASCADE study was a pragmatic cluster RCT, with integral process and economic evaluations, of a complex(More)
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