Mary Leonora Disis

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The importance of CD4+ Th1 cells during the effector phase of the antitumor response has been overshadowed by emphasis on CD8+ cytotoxic T lymphocytes (CTLs). To determine their respective functions, we purified antigen-primed T cells from tumor-draining lymph nodes and separately activated CD4+ and CD8+ subsets in vitro. Adoptive transfer of CD4+ T(More)
University of Washington, Department of Medicine, Division of Medical Genetics, Seattle, WA 98195, USA University of Washington, Department of Pathology, Seattle, WA 98195 University of Washington, Department of Medicine, Division of Oncology, Seattle, WA 98195 Fred Hutchinson Cancer Research Center, Seattle, WA 98195, USA Shanghai Sunway Biotech, No.1150,(More)
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