Mary L Chavez

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BACKGROUND Traditional nonsteroidal anti-inflammatory drugs (NSAIDs) such as diclofenac, ibuprofen, naproxen, and related agents are nonselective inhibitors of both cyclooxygenase-1 (COX-1) and COX-2, which catalyze prostaglandin synthesis. This inhibition accounts not only for the analgesic, anti-inflammatory, and antipyretic effects of these agents, but(More)
Due to the growing use of herbals and other dietary supplements healthcare providers and consumers need to know whether problems might arise from using these preparations in combination with conventional drugs. However, the evidence of interactions between natural products and drugs is based on known or suspected pharmacologic activity, data derived from in(More)
A 73-year-old man recently attended his local USToo International prostate cancer support group and during the meeting several members were discussing using PC-SPES for treatment of their prostate cancer. The patient's history is significant for prostate cancer and as a result he had a radical prostatectomy. Two years ago, he relapsed with bone metastases(More)
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