Mary Jo Mount Crooks

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Free and total ibuprofen levels in serum and synovial fluid (SF) were determined in one male and 14 female arthritic patients (mean age 56 yr, range 19 to 77) after 400 mg three times daily for 2 days. Free drug was separated by ultrafiltration and assayed by a new highly sensitive and precise gas chromatographic-mass spectrometric technique. Total protein(More)
A new method of treating dynamic dialysis data to obtain binding parameters for drug-macromolecule interactions is presented. This method allows the determination of binding parameters directly from dialysis data according to a theoretical model. It is not necessary to determine the dialysis rate constant accurately in a separate experiment, and bias is not(More)
Copyright © 2016 National Association of Orthopaedic Nurses. Unauthorized reproduction of this article is prohibited. ONC Jonathan Abania Jisha Abraham Susanne Abramson Melissa Adams Stephanie Albert Sara Alferez Lisa Alvarez Cristy Amundgaard Lisa Maurine Andersen Susan M. Anderson Elizabeth A. Anderson Lizeth Anderson-Raciti Laurie Antonini Nicole(More)