Mary J. George

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Research on the effects of antidepressant/ antipanic drugs in animal models of anxiety has yielded equivocal results, even after chronic drug regimens. In contrast, we found that the antidepressant/antipanic drug phenelzine, given acutely, produced a clear anxiolytic effect in the elevated plus-maze, a widely-used animal model of "anxiety" that is primarily(More)
The ideal design of an airplane should include built-in sensors that are pre-blended in the perfect aerodynamic shape. Each built-in sensor is expensive to blend in and requires continuous maintenance and data processing, so we would like to use as few sensors as possible. The ideal formulation of the corresponding optimization problem is, e.g., to minimize(More)
Gravid Sprague-Dawley CD (VAF) rats received 50 mg/kg (d,l)-methamphetamine (MA) HCl (expressed as free base, N = 15) or distilled water (N = 6) by SC injection x 2/day in a 3 ml/kg volume on embryonic (E) days 7-12. Control rats were pair-fed to MA-exposed dams on days E7-18. No control dams failed to deliver; however, of 15 MA-exposed dams 4 did not(More)
One of the most important characteristics of the plane is its weight: every pound shaved oo the plane means a pound added to the carrying ability of this plane. As a result, planes are made as light as possible , with its \skin" as thin as possible. However, the thinner the layer, the more vulnerable is the resulting structure to stresses and faults, and a(More)
The inverse problem is usually diicult because the signal (image) that we want to reconstruct is weak. Since it is weak, we can usually neglect quadratic and higher order terms, and consider the problem to be linear. Since the problem is linear, methods of solving this problem are also, mainly, linear (with the notable exception of the necessity to take(More)
To understand some of the mechanisms underlying the neuroendocrine and neurochemical changes associated with aging, we administered the serotonin [5-hydroxytryptamine (5-HT)] releaser and reuptake inhibitor d-fenfluramine (d-FEN; 0.0, 0.2, or 0.6 mg/kg/day, p.o) for 30-38 days to young (4 months) and old (22 months) F344 male rats. Rats were stressed by(More)
Flight is a very stressful experience for materials and structures. As a result, even small faults in aerospace structures can lead to catastrophic results. It is therefore desirable to test the structural integrity of an airplane and/or a space structure before the ight (and ideally, in-ight as well) and detect potential faults. In this paper, we show that(More)
Celestial bodies such as galaxies, stellar clusters, planetary systems, etc., have diierent geometric shapes (e.g., galaxies can be spiral or circular, etc.). Usually, complicated physical theories are used to explain these shapes; for example, several dozen diierent theories explain why many galaxies are of spiral shape. Some rare shapes are still diicult(More)
To elucidate some of the mechanisms underlying the neuroendocrine and neurochemical changes associated with age in female rats, we administered the serotonin (5-HT) releaser and reuptake inhibitor, d-fenfluramine (d-FEN; 0.0 or 0.6 mg/kg/day, PO) for 30-38 days to young (4 month) and old (21 month) F-344 female rats. Animals were placed into a novel open(More)