Mary Gandossini

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Simultaneous measurement of neutrophil migration, phagocytic activity, candidacidal and bactericidal activity were made during quadruple chemotherapy of advanced Hodgkin's disease (HD). Measurements were also made in normal individuals, hospital patients not on chemotherapy, untreated patients with advanced HD and patients off chemotherapy for over a year.(More)
Whole-blood techniques were used to study neutrophil migration and uptake and killing of Candida in patients with advanced (Stages IIIB and IV) Hodgkin's disease (HD). In order to assess the effect of therapy on neutrophil function, 17 patients were studied either before treatment or on days 1, 8 and 14 of successive cycles of chemotherapy. Neutrophil(More)
Simultaneous measurements of leucocyte numbers and function have been made during combination chemotherapy for advanced Hodgkin's disease. There was a marked fall in the numbers of circulating mononuclear cells during the chemotherapy cycle in many patients. The migratory, phagocytic, candidacidal, and bactericidal activities of polymorphs and monocytes(More)
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