Mary-Ellen Yarker

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OBJECTIVE To determine whether isotretinoin (or 13-cis-retinoic acid) decreases the risk of second primary cancers in patients previously treated for cure of head and neck squamous cell carcinoma. DESIGN Randomized, double-blind, placebo-controlled trial. SETTING Two head and neck multidisciplinary cancer clinics in university teaching hospitals taking(More)
There is evidence from previous studies of small numbers of children who received cytotoxic therapy for cancer, that they may develop increased numbers of melanocytic naevi (moles), the strongest known risk factors for melanoma. Our aim was to investigate a large number of survivors of childhood cancer in order to test the hypothesis that they have more(More)
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