Mary E. Wikswo

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Implemented in 2009, the National Outbreak Reporting System provides surveillance for acute gastroenteritis outbreaks in the United States resulting from any transmission mode. Data from the first 2 years of surveillance highlight the predominant role of norovirus. The pathogen-specific transmission pathways and exposure settings identified can help inform(More)
During 2012, global detection of a new norovirus (NoV) strain, GII.4 Sydney, raised concerns about its potential effect in the United States. We analyzed data from NoV outbreaks in 5 states and emergency department visits for gastrointestinal illness in 1 state during the 2012-13 season and compared the data with those of previous seasons. During August(More)
BACKGROUND Norovirus is a leading cause of acute gastroenteritis (AGE). Noroviruses bind to gut histo-blood group antigens (HBGAs), but only 70%-80% of individuals have a functional copy of the FUT2 ("secretor") gene required for gut HBGA expression; these individuals are known as "secretors." Susceptibility to some noroviruses depends on FUT2 secretor(More)
treatment or prevention of mucositis, earlier detection and identification of isolates, and revision of current anti-microbial drug protocols for empiric treatment of neutropenic fever. and the staff of the Blood and Bone Marrow Transplant Program for their time and expertise and for providing data for patients, the transplant program, and microbiologic(More)
Awareness of non-O157 Shiga toxin-producing Escherichia coli (non-O157 STEC) as a food safety concern has increased recently. In October 2009, a CΉφΉϸ͊΢͞μ P͊φΉφΉΩ΢ ϭ̮μ ͔ΉΛ͊͆ ϭΉφΆ φΆ͊ ΔΊD!͞μ Food Safety and Inspection Service (FSIS) to declare all enterohemorrhagic (EHEC) Shiga toxin-producing serotypes of Escherichia coli (STEC), including non-O157(More)
BACKGROUND In 2010, researchers using novel laboratory techniques found that US-licensed rotavirus vaccines contain DNA or DNA fragments from Porcine circovirus (PCV), a virus common among pigs but not believed to cause illness in humans. We sought to understand pediatricians' and mothers' perspectives on this finding. METHODS We conducted three(More)
To the Editor: Group A rotaviruses (RVAs) are a leading cause of acute gastroenteritis-associated deaths among children <5 years of age in developing countries (1). The genome of RVA consists of 11 double-stranded RNA segments that code for 11 or 12 viral proteins (VP1– VP4, VP6, VP7, nonstructural protein 1 [NSP1]–NSP5/6) (2). In 2008, the Rotavirus(More)
  • Maureen A. Leahy, Julia C. Martinroe, Stephen R. Spriggs, Terraye M. Starr, Mary E. Wikswo
  • 2012
Front cover photo: Two images, which include 1) norovirus and 2) hand washing. Abstract Problem/Condition: Approximately 179 million cases of acute gastroenteritis (AGE) occur in the United States each year, and outbreaks of AGE are a substantial public health problem. Although CDC has conducted national surveillance for waterborne and foodborne AGE(More)
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