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Noninvasive imaging of cell death using an Hsp90 ligand.

• Danielle N Park, Anthony S. Don, +12 authors Philip J Hogg
• Journal of the American Chemical Society
• 2011

Cell death plays a central role in normal physiology and in disease. Common to apoptotic and necrotic cell death is the eventual loss of plasma membrane integrity. We have produced a small… (More)

Characterization of novel histidine-tagged Tat-peptide complexes dual-labeled with (99m)Tc-tricarbonyl and fluorescein for scintigraphy and fluorescence microscopy.

• Kristin E Bullok, Mary E Dyszlewski, Julie L. Prior, Christina M. Pica, Vijay Sharma, David R. Piwnica-Worms
• Bioconjugate chemistry
• 2002

To enable concurrent whole body scintigraphy and direct imaging of subcellular localization of permeation peptides, dual-labeled Tat-peptides useful for both radiometric analysis and fluorescence… (More)

Evidence for a plasma membrane-mediated permeability barrier to Tat basic domain in well-differentiated epithelial cells: lack of correlation with heparan sulfate.

• Stefania Violini, Vijay Sharma, Julie L. Prior, Mary E Dyszlewski, David R. Piwnica-Worms
• Biochemistry
• 2002

Membrane permeation peptides, such as Tat basic domain, have emerged as useful membrane transduction agents with potential utility in therapeutic delivery and diagnostic imaging. While generally… (More)

Fluorescence-enhanced europium-diethylenetriaminepentaacetic (DTPA)-monoamide complexes for the assessment of renal function.

• Lori K Chinen, Karen P. Galen, +7 authors Raghavan Rajagopalan
• Journal of medicinal chemistry
• 2008

Real-time, noninvasive assessment of glomerular filtration rate (GFR) is essential not only for monitoring critically ill patients at the bedside, but also for staging and monitoring patients with… (More)

Noninvasive Molecular Imaging of Cell Death in Myocardial Infarction using 111In-GSAO

• Nobuhiro Tahara, H. Reinier Zandbergen, +13 authors Jagat P Narula
• Scientific reports
• 2014

Acute insult to the myocardium is associated with substantial loss of cardiomyocytes during the process of myocardial infarction. In this setting, apoptosis (programmed cell death) and necrosis may… (More)

Characterization of a novel 99mTc-carbonyl complex as a functional probe of MDR1 P-glycoprotein transport activity.

• Mary E Dyszlewski, Helen M Blake, Julie L Dahlheimer, Christina M. Pica, David R. Piwnica-Worms
• Molecular imaging
• 2002

Multidrug resistance (MDR) mediated by overexpression of MDR1 P-glycoprotein (Pgp) is one of the best characterized barriers to chemotherapy in cancer patients. Furthermore, the protective function… (More)

Noninvasive Molecular Imaging of Cell Death in Myocardial Infarction using In-GSAO

• Reinier de Haas, Hans Petrov, +20 authors Jagat P Narula
• 2017

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