Mary C Misley

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ABSTRACT. This study was designed to assess potential differences in ventilation homogeneity related to growth. One hundred thirty-three healthy subjects representing four stages of growth were studied: group 1, preschool, ages 34–74 months; group 2, preadolescent, ages 8–10 yr; group 3, postpubertal, ages 15–17 yr; group 4, young adult, ages 26–40 yr.(More)
The purpose of this study was to examine the variability and possible uses of partial maximal expiratory flow-volume curves as a measurement of lung function in young children. Repeated partial flow-volume curves followed by measurement of resting lung volume were obtained from 45 healthy children and 12 with generally mild lung disease caused by cystic(More)
Moment analysis (MA) of MBNW could in theory be a good method of quantifying ventilation inhomogeneity in young children since it requires only quiet breathing of oxygen for <2 minutes and the results are independent of breathing pattern or lung volume. We have developed the software required for on-line MA of MBNW and have performed duplicate studies on 36(More)
This study was designed to explore the relationship between ventilation non-uniformity, as assessed by moment analysis of nitrogen washout, and airways obstruction, as assessed by spirometry, in children with asthma. Moment ratios derived from the multibreath washout curves in asthmatics were significantly higher than those obtained from healthy controls (P(More)
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