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PURPOSE The goal of the computer program Adjuvant! is to allow health professionals and their patients with early breast cancer to make more informed decisions about adjuvant therapy. METHODS Actuarial analysis was used to project outcomes of patients with and without adjuvant therapy based on estimates of prognosis largely derived from Surveillance,(More)
OBJECTIVES Women in impoverished inner-city neighborhoods are at high risk for contracting HIV. A randomized, multisite community-level HIV prevention trial was undertaken with women living in 18 low-income housing developments in 5 US cities. METHODS Baseline and 12-month follow-up population risk characteristics were assessed by surveying 690 women at(More)
BACKGROUND Irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD) are chronic conditions affecting millions of individuals in the United States. The symptoms are well-documented and can be debilitating. How these chronic gastrointestinal (GI) conditions impact the daily lives of those afflicted is not well documented, especially from a(More)
BACKGROUND Melanoma is external and potentially detectable by many persons but little is known about who first discovers these lesions. An understanding of discovery patterns can shape future public and professional education programs. OBJECTIVE Our purpose was to assess patterns of melanoma discovery and to determine the patients' role in finding their(More)
BACKGROUND The objective of this study is to examine the reasoning behind donation decisions of donor-eligible patients' next-of-kin. Cases were identified through chart review at hospitals in Ohio and Pennsylvania. Family decision makers of donor-eligible patients (N = 420) were interviewed to understand decisions regarding organ donation. METHODS(More)
CONTEXT Families' understanding of brain death may be a factor that contributes to decisions regarding organ donation. OBJECTIVE To examine factors related to families' understanding of brain death and how those factors affect families' decisions about organ donation. DESIGN Chart reviews were conducted on all deceased patients at 9 trauma hospitals.(More)
OBJECTIVE To determine whether persons with melanoma were integrated into the health care system prior to diagnosis. DESIGN Population-based survey by mailed questionnaire. PATIENTS/PARTICIPANTS 216 persons with malignant melanoma diagnosed in Massachusetts in 1986. MAIN RESULTS Of the 216 cases, 87% stated that they had regular physicians, 63% had(More)
BACKGROUND African Americans undergo joint replacement less often than do white persons. The authors studied African-American perceptions and preferences for the care of knee and hip pain. METHODS 10 focus groups were conducted in an inner city community. Participants, older persons with chronic knee or hip pain, were asked to discuss their perceptions(More)
OBJECTIVES This study describes the prevalence and predictors of human immunodeficiency virus (HIV) risk behaviors among women living in low-income, inner-city housing developments. METHODS Anonymous questionnaires were administered to 671 women living in 10 inner-city, low-income housing developments in five US cities to determine their levels of HIV(More)
BACKGROUND Candidates for specialty drugs, the fastest growing and costliest pharmaceuticals, typically originate with primary care referrals. However, little is known about what drives such referrals-especially for large populations such as short, otherwise normal children (idiopathic short stature). Recent expanded approval of growth hormone (GH) makes(More)