No depression screening tool is validated for use in cases of cerebral glioma. To address this, we studied the operating characteristics of the Hospital Anxiety and Depression Scale (Depression subscale) (HAD-D), the Patient Health Questionnaire-9 (PHQ-9), and the Distress Thermometer (DT) in glioma patients.We conducted a twin-center prospective… (More)
BACKGROUND Relatively little is known about the frequency, longitudinal course, independent associations, and reported causes of emotional distress in adults with primary cerebral glioma. We aimed to describe these features in an observational study. METHODS This was a twin-center prospective cohort study. Eligible adults were those with a new… (More)
When screening for depression in glioma patients, the utility of proxy carer report is unknown. We studied how patients and proxies differed in the frequency, severity and agreement of reported depressive symptoms, the external validity of these reports, and whether patient-proxy agreement was associated with cognitive function. This was a cross-sectional… (More)
The superconducting upgrade of the REX-ISOLDE radioactive ion beam (RIB) post-accelerator at CERN will utilise a compact lattice comprising quarter-wave res-onators (QWRs) and solenoids, accelerating beams in the mass range 2.5 < A/q < 4.5 to over 10 MeV/u. The short and independently phased quarter-wave structures allow for the acceleration of RIBs over a… (More)
Haematology parameters (N = 24) and serum biochemistry parameters (N = 35) were determined for wild Eurasian beavers (Castor fiber), between 6 months - 12 years old. Of the population tested in this study, N = 18 Eurasian beavers were from Norway and N = 17 originating from Bavaria but now living extensively in a reserve in England. All blood samples were… (More)
Global climate change and increases in sea levels will affect coastal marine communities. The conservation of these ecologically important areas will be a challenge because of their wide geographic distribution, ecological diversity and species richness. To address this problem, we need to better understand how the genetic variation of the species in these… (More)
Perspectives 387 Response to Bellini's (2007) Commentary on Lichten and Simon's (2007) " Defining Mental Retardation: A Matter of Life or Death " .