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Hypohydration reduces exercise performance and thermoregulatory capacity in the heat. Hyperhydration prior to exercise may decrease, delay, or eliminate the detrimental effects of hypohydration. The rapid clearance of excess fluid makes hyperhydration of subjects with common beverages difficult. Glycerol, a natural metabolite which is rapidly absorbed, has(More)
Glycerol was tested as an agent to promote hyperhydration of male and female subjects. Series I experiments involved ingesting 0.5, 1.0, or 1.5 g glycerol/kg body wt and within 40 min drinking 0.1% NaCl, 21.4 ml/kg. In series II, 1.0 g glycerol/kg body wt was ingested at time 0, and 25.7 ml/kg of 0.1% NaCl was ingested over a 3.5-h period. Experiments were(More)
BACKGROUND AND PURPOSE Presyncope, characterized by symptoms and signs indicative of imminent syncope, can be aborted in many situations before loss of consciousness occurs. The plasticity of cerebral autoregulation in healthy humans and its behavior during this syncopal prodrome are unclear, although systemic hemodynamic instability has been suggested as a(More)
The effects of glycerol ingestion (GEH) on hydration and subsequent cycle ergometer submaximal load exercise were examined in well conditioned subjects. We hypothesized that GEH would reduce physiologic strain and increase endurance. The purpose of Study I (n = 11) was to determine if pre-exercise GEH (1.2 gm/kg glycerol in 26 ml/kg solution) compared to(More)
Glycerol solutions are a safe, effective means to achieve a long-term state of hyperhydration. The effects of glycerol-induced hyperhydration (GIH) on the total body water (TBW), extracellular fluid (ECF), plasma volume (PV), intracellular fluid (ICF), and interstitial fluid (ISF) were investigated in the rat. Ten rats were intragastrically administered(More)
A review of the metabolism of hibernators supports the argument that protein utilization is an essential aspect of hibernation. Several lines of evidence in support of this hypothesis are discussed, including (1) the field preferences of some hibernators for a diet rich in protein prior to hibernation, (2) the gluconeogenic maintenance of glycogen stores(More)