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Purpose. To determine and compare the relationship between in vivo oral absorption in humans and the apparent permeability coefficients (P app ) obtained in vitro on two human intestinal epithelial(More)
The glucuronidation of the AT1 nonpeptide angiotensin II receptor antagonist, SR 47436 (BMS 186295), was investigated in hepatic microsomes prepared from various species, i.e., Sprague-Dawley rat,(More)