Martina Michalikova

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Spikelets are small spike-like depolarizations that can be measured in somatic intracellular recordings. Their origin in pyramidal neurons remains controversial. To explain spikelet generation, we propose a novel single-cell mechanism: somato-dendritic input generates action potentials at the axon initial segment that may fail to activate the soma and(More)
Spikelets are brief, spike-like depolarizations of small amplitude (< 20 mV) that can be measured in somatic intracellular recordings. Prominent spikelet activity was demonstrated in hippocampal CA1 pyramidal neurons in awake behaving [1,2] and anesthetized animals [3]. However, spikelets are rarely observed in vitro, and basic mechanisms underlying their(More)
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