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BACKGROUND Elderly persons frequently complain about problems with speech understanding especially in complex acoustic situations. Besides hearing impairment the decline of cognitive functions might explain these problems. METHODS In 12 normal hearing young subjects and 14 elderly listeners with extraordinarily good hearing speech perception was measured(More)
OBJECTIVE To examine the prevalence of auditory neuropathy/synaptopathy (AN/AS) in a cohort of children with profound hearing loss. METHODS From 1997 until 2004, 5190 children, aged 1-15 years, whose hearing ability was uncertain or who had risk factors for hearing impairment were investigated with subjective and objective hearing tests. Three thousand(More)
We have identified a consanguineous family from Morocco segregating autosomal recessive congenital progressive hearing loss (ARNSHL) and retinal degeneration. Detailed clinical investigation of the six siblings revealed combined severe cone-rod dystrophy (CORD) and severe/profound hearing impairment in two of them, while there is isolated CORD in three and(More)
Human nasal respiratory cells lose cilia in submerged cultures. This study compares the effect of extracellular matrix (ECM) molecules of the basal lamina on ciliogenesis in submerged cell cultures to ECM-free suspension cultures. Respiratory mucosa of nasal turbinates was the routine source for the cultures of nasal epithelial cells. For the submersion(More)
OBJECTIVE The purpose of this study was to assess the influence of dynamic compression on directional hearing in the frontal horizontal plane. DESIGN Compression schemes with various compression ratios and attack times were created by using a digital signal processor. The influence of compression on isolated interaural level differences (ILDs) and(More)
OBJECTIVE To introduce conjoint analysis (CA) as a method to explain choice decisions of hearing aid users and to measure the contributions of different hearing aid attributes involved. DESIGN The study was conducted using CA, a method that is well established in marketing, but has not been used for hearing aid research. CA examines the contributions(More)
Speech recognition in a multi-talker situation poses high demands on attentional and other central resources. This study examines the relationship between age, cognition and speech recognition in tasks that require selective or divided attention in a multi-talker setting. Two groups of normal-hearing adults (one younger and one older group) were asked to(More)
PURPOSE To examine the association of cognitive function, age, and hearing loss with clinically assessed hearing aid benefit in older hearing-impaired persons. METHODS Hearing aid benefit was assessed using objective measures regarding speech recognition in quiet and noisy environments as well as a subjective measure reflecting everyday situations(More)
PURPOSE The purpose of this study was to investigate the relationship of cognitive functions (i.e., working memory [WM]) and speech recognition against different background maskers in older individuals. METHOD Speech reception thresholds (SRTs) were determined using a matrix-sentence test. Unmodulated noise, modulated noise (International Collegium for(More)
The purpose of this study was to examine the effects of altering the fundamental frequency (F0) on perception of prosody and speaker gender in both normal-hearing listeners and cochlear implant (CI) recipients. Tests with natural speech and defined modifications of the F0 were performed, and the resulting changes in perception were measured. Compared to the(More)