Martin W Howell

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PURPOSE To evaluate whether HLA genotypes are associated with age-related macular degeneration (AMD). METHODS HLA class I-A, -B, and -Cw and class II DRB1 and DQB1 principal allele groups were genotyped in two stages: initially for principal allele groups in a cohort of 100 AMD cases and 92 control subjects, and then, in the next 100 cases and controls(More)
[1] Water column stratification increased at climatic transitions from cold to warm periods during the late Quaternary and led to anoxic conditions and sapropel formation in the deep eastern Mediterranean basins. High-resolution data sets on sea-surface temperatures (SST) (estimated from U 37 k 0 indices) and d 18 O of planktonic foraminifer calcite (d 18 O(More)
Forecasting levels of stocks held by manufacturing industry is problematic. Stocks are the most volatile component of GDP. The data itself is subject to chronic revision. Yet, forecasting inventory changes in the supply chain is crucial for firms trying to manage output. The paper reports a successful approach to forecasting UK manufacturing stock behaviour(More)
OBJECTIVES Eliciting preferences and trade-offs that patients may make to achieve important outcomes, can assist in developing patient-centred research and care. The pilot study aimed to test the feasibility of a case 2 best-worst scaling survey (BWS) to elicit recipient with kidney transplantation preferences after transplantation. DESIGN Preferences for(More)
BACKGROUND Although advances in treatment have dramatically improved short-term graft survival and acute rejection in kidney transplant recipients, long-term graft outcomes have not substantially improved. Transplant recipients also have a considerably increased risk of cancer, cardiovascular disease, diabetes, and infection, which all contribute to(More)
These guidelines to best practice in stem cell donor selection will change with time. The guidelines present collective opinions from a numerous experts in the field and do not have the force of law. The guide is to be used as a tool towards best practice for progenitor cell donor selection and should be interpreted as thus. The guidelines present opinions(More)
(Suggestions are based primarily on Level III and IV evidence) • An accurate assessment of the glomerular filtration rate (GFR) should be undertaken in all potential donors. The benefit of obtaining a directly measured GFR (thought to be more accurate) over an estimated GFR, has not been proven in live donors (refer to CARI guidelines titled 'Use of(More)
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