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BACKGROUND Maternal mortality in Africa has changed little since 1990. We developed a mathematical model with the aim to assess whether improved community-based access to life-saving drugs, to augment a core programme of health-facility strengthening, could reduce maternal mortality due to post-partum haemorrhage or sepsis. METHODS We developed a(More)
Patient safety will benefit from an approach to human error that examines systemic causes, rather than blames individuals. This study describes a direct observation methodology, based on a threat and error model, prospectively to identify types and sources of systems failures in paediatric cardiac surgery. Of substantive interest were the range, frequency(More)
BACKGROUND Identifying and addressing the requirements of cancer survivors is currently a high priority for the NHS, yet little is known about the population of cancer survivors in the United Kingdom. METHODS Data from cancer registries in England, Northern Ireland, Scotland and Wales were analysed to provide limited-duration prevalence estimates for(More)
OBJECTIVES To investigate the variability of patients' length of stay in intensive care after cardiac surgery. To investigate potential interactions between such variability, booked admissions, and capacity requirements. DESIGN Mathematical modelling study using routinely collected data. SETTING A cardiac surgery department. SOURCE OF DATA Hospital(More)
BACKGROUND There are currently two million cancer survivors in the United Kingdom, and in recent years this number has grown by 3% per annum. The aim of this paper is to provide long-term projections of cancer prevalence in the United Kingdom. METHODS National cancer registry data for England were used to estimate cancer prevalence in the United Kingdom(More)
BACKGROUND The fifth Millennium Development Goal target for 90% of births in low and middle income countries to have a skilled birth attendant (SBA) by 2015 will not be met. In response to this, policy has focused on increasing SBA access. However, reducing maternal mortality also requires policies to prevent deaths among women giving birth unattended. We(More)
BACKGROUND In the United Kingdom, clinical guidelines recommend that services for depression and anxiety should be structured around a stepped care model, where patients receive treatment at different 'steps,' with the intensity of treatment (i.e., the amount and type) increasing at each step if they fail to benefit at previous steps. There are very limited(More)
OBJECTIVE To implement routine in-house monitoring of risk-adjusted 30-day mortality following paediatric cardiac surgery. DESIGN Collaborative monitoring software development and implementation in three specialist centres. PATIENTS AND METHODS Analyses incorporated 2 years of data routinely audited by the National Institute of Cardiac Outcomes Research(More)
Outcomes following paediatric cardiac surgery have long been the subject of clinical , regulatory, media and public scrutiny. There are several reasons for this. The work is among the most technically challenging , resource intensive and emotionally charged clinical activity undertaken. In the UK, past events, public inquiries and intentions to reduce the(More)