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BACKGROUND The feasibility, safety, and efficacy of prolonged use of an artificial beta cell (closed-loop insulin-delivery system) in the home setting have not been established. METHODS In two… Expand
Summary Background Tight control of blood glucose concentration in people with type 1 diabetes predisposes to hypoglycaemia. We aimed to investigate whether day-and-night hybrid closed-loop insulin… Expand
Numerous milestones mark the advance of diabetes care since the discovery of insulin in 1921. Glucose monitoring has progressed from urine to blood to interstitial fluid measurements every 5-15… Expand
Type 1 diabetes mellitus (T1DM) represents 5–10% of diabetes cases worldwide. The incidence of T1DM is increasing, and there is no immediate prospect of a cure. As such, lifelong management is… Expand
Abstract Objective To evaluate the efficacy and safety of artificial pancreas treatment in non-pregnant outpatients with type 1 diabetes. Design Systematic review and meta-analysis of randomised… Expand
Objective: The objective was to explore psychosocial experiences of closed loop technology for adults, children, and adolescents with type 1 diabetes and their parents taking part in two multicenter,… Expand
The ISPAD Hypoglycemia guidelines have been harmonized with the International Hypoglycemia Study Group (IHSG). This article is protected by copyright. All rights reserved.
OBJECTIVE We aimed to assess the feasibility and safety of hybrid closed-loop insulin delivery in children with type 1 diabetes aged 1–7 years as well as evaluate the role of diluted insulin on… Expand
OBJECTIVE To evaluate feasibility, safety, and efficacy of day-and-night hybrid closed-loop insulin delivery in adolescents with type 1 diabetes under free-living conditions without remote monitoring… Expand