Martin T. Morgan

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The effect of deleterious mutations on neutral molecular variation.

Brian Charlesworth, Martin T. Morgan, Deborah Charlesworth
Genetics
1993

Selection against deleterious alleles maintained by mutation may cause a reduction in the amount of genetic variability at linked neutral sites. This is because a new neutral variant can only remain… (More)

Genome-wide MyoD binding in skeletal muscle cells: a potential for broad cellular reprogramming.

Y. W. Cao, Zizhen Yao, +9 authors Stephen J. Tapscott
Developmental cell
2010

Recent studies have demonstrated that MyoD initiates a feed-forward regulation of skeletal muscle gene expression, predicting that MyoD binds directly to many genes expressed during differentiation.… (More)

Bacterial Communities in Women with Bacterial Vaginosis: High Resolution Phylogenetic Analyses Reveal Relationships of Microbiota to Clinical Criteria

Sujatha Srinivasan, Noah G. Hoffman, +8 authors David N. Fredricks
PloS one
2012

BACKGROUND Bacterial vaginosis (BV) is a common condition that is associated with numerous adverse health outcomes and is characterized by poorly understood changes in the vaginal microbiota. We… (More)

Evolution of a small-muscle polymorphism in lines of house mice selected for high activity levels.

Theodore Garland, Martin T. Morgan, +4 authors Patrick A. Carter
Evolution; international journal of organic…
2002

To study the correlated evolution of locomotor behavior and exercise physiology, we conducted an artificial selection experiment. From the outbred Hsd:ICR strain of Mus domesticus, we began eight… (More)

The pattern of neutral molecular variation under the background selection model.

Deborah Charlesworth, Brian Charlesworth, Martin T. Morgan
Genetics
1995

Stochastic simulations of the infinite sites model were used to study the behavior of genetic diversity at a neutral locus in a genomic region without recombination, but subject to selection against… (More)

Genetic loads and estimates of mutation rates in highly inbred plant populations

ESTIMATES of the rate of mutation to mildly deleterious alleles are fundamental to the testing of theories of the maintenance of sexual reproduction1 and recombination2,3. There are, however, few… (More)

Transposable element number in mixed mating populations.

Martin T. Morgan
Genetical research
2001

Theoretical population genetic studies of transposable elements focus almost exclusively on random mating species, whereas many plants reproduce through partial or substantial self-fertilization.… (More)

INBREEDING DEPRESSION, GENETIC LOAD, AND THE EVOLUTION OF OUTCROSSING RATES IN A MULTILOCUS SYSTEM WITH NO LINKAGE.

Deborah Charlesworth, Martin T. Morgan, Brian Charlesworth
Evolution; international journal of organic…
1990

We studied deterministic models of multilocus systems subject to mutation-selection balance with all loci unlinked, and with multiplicative interactions of the loci affecting fitness, in partially… (More)

Using genetic markers to directly estimate male selection gradients.

Martin T. Morgan, Jeffrey K Conner
Evolution; international journal of organic…
2001

We present an analysis of Raphanus raphanistrum and simulations illustrating the utility of directly estimating male phenotypic selection gradients using genetic markers. The method offers a much… (More)

Explaining phenotypic selection on plant attractive characters: male function, gender balance or ecological context?

Tia-Lynn Ashman, Martin T. Morgan
Proceedings. Biological sciences
2004

It is widely agreed that the flowers of hermaphrodite plants evolve in response to selection acting simultaneously through male and female sexual functions, but we know very little about the pattern… (More)

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