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Regional brain volumes were measured in 21 patients with progressive supranuclear palsy (PSP), 17 patients with Parkinson's disease and 23 controls using 3D MRI-based volumetry. Cortical, subcortical and ventricular volume measures were correlated with global indices of motor disability and cognitive disturbance. All MRI measures, including hippocampal(More)
In clinical practice, research, and increasingly health surveillance, planning and costing, there is a need for high quality information to determine comorbidity information about patients. Electronic, routinely collected healthcare data is capturing increasing amounts of clinical information as part of routine care. The aim of this study was to assess the(More)
BACKGROUND The mainstay of treatment for acute asthma in children is nebulised beta 2-adrenergic agents such as salbutamol, given with corticosteroids. However, penetration of the drug to the small airways is impeded by obstruction so intravenous salbutamol may be more effective. We assessed the use of intravenous salbutamol in the management of children(More)
PURPOSE To assess the utility of spiral computed tomography (CT) with three-dimensional reconstruction in defining aneurysms of the Circle of Willis. METHODS Eighty-one patients with angiographic or surgical correlation were studied between 1993 and 1995, with surface rendered reconstructions of the arteries of the Circle of Willis. RESULTS Spiral CT(More)
A diabetic man suffering from a hypoglycaemic attack presented to our hospital. Magnetic resonance imaging (MRI) findings were grossly abnormal and difficult to interpret. The computed tomographic appearance simulated multiple infarctions. The MRI appearance simulated a space occupying lesion. Literature review of the radiology and the pathophysiology of(More)
Chordomas of the cervical spine are rare. A case of a cervical chordoma is described. The initial radiological misinterpretation was due to the unavailability of CT myelography or MRI. Treatment of this disease is difficult, with multiple operations often required. Tumour bulk at diagnosis, completeness of surgical excision, availability of radiotherapy and(More)
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