Martin Siegel

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Previous studies indicate that the distribution of corticoamygdaloid neurons in the rat prelimbic (PL) and infralimbic (IL) cortices overlaps with the distribution of neurons projecting to the contralateral medial prefrontal cortex (MPC), insular cortex, mediodorsal thalamus, and dorsal medulla. In view of the poorly differentiated cytoarchitecture of PL(More)
The predicted spectral phase of a fiber continuum pulsed source rigorously quantified by the scalar generalized nonlinear Schrödinger equation is found to be in excellent agreement with that measured by multiphoton intra-pulse interference phase scan (MIIPS) with background subtraction. This cross-validation confirms the absolute pulse measurement by MIIPS(More)
Placing animals in an unfamiliar environment triggers at least two major reactions: (1) a heightened state of arousal, fear, or distress and (2) a sharp increase in information processing as the animal attempts to learn about its new environment. These changes could have a profound effect on the way in which the animal reacts to the types of extraneous(More)
We quantitatively predict the observed continuum-like spectral broadening in a 90-mm weakly birefringent all-normal dispersion-flattened photonic crystal fiber pumped by 1041-nm 229-fs 76-MHz pulses from a solid-state Yb:KYW laser. The well-characterized continuum pulses span a bandwidth of up to 300 nm around the laser wavelength, allowing high spectral(More)
Rats 16 to 60 days of age were placed in an unfamiliar environment either alone or in the presence of an anesthetized lactating dam. Rats of all ages show a dramatic increase in fear, as measured by heart rate (HR), when placed alone in an unfamiliar environment. Adult rats, however, show a rapid decline in heart rate during the course of a 90-min session,(More)
The effects of naloxone on social play and feeding behaviors of postweanling and adult Long-Evans hooded rats were studied. Administration of 1.0, 5.0, or 10.0 mg/kg naloxone reduced play in a dose-related fashion. The effects of a 5.0-mg/kg dose of naloxone could be detected at least 3 h after administration, in terms of both a decrease in social behavior(More)
In two experiments the effects of the presence of an anesthetized lactating dam on the developing rat's response to a series of mildly painful shocks was examined. Both cardiac and behavioral responses to the shock stimulus were recorded. In the first experiment animals were tested at either 16, 20, or 24 days of age. The presence of the anesthetized dam(More)
The effects of large and small housing environments as well as naloxone on social play (as defined by pinning behavior) in isolated postweanling male rats were investigated. Animals housed in small cages played significantly more than those housed in larger cages. This effect was not observed when cage size was reversed. Administration of 0.5, 1.0, and 5.0(More)
Vibrational spectroscopy has been widely applied in different fields due to its label-free chemical-sensing capability. Coherent anti-Stokes Raman scattering (CARS) provides stronger signal and faster acquisition than spontaneous Raman scattering, making it especially suitable for molecular imaging. Coherently-controlled single-beam CARS simplifies the(More)