Martin Schnell

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Light scattering at nanoparticles and molecules can be dramatically enhanced in the 'hot spots' of optical antennas, where the incident light is highly concentrated. Although this effect is widely applied in surface-enhanced optical sensing, spectroscopy and microscopy, the underlying electromagnetic mechanism of the signal enhancement is challenging to(More)
A comparison of dynamic results of a multi-echo contrast-enhanced perfusion study obtained from a keyhole imaging experiment and the results from low-resolution updates is presented. If, for each dynamic state, a separate reference image exists, high spatial resolution in the dynamic results can be preserved through keyhole imaging. If only one reference(More)
Holography has paved the way for phase imaging in a variety of wide-field techniques, including electron, X-ray and optical microscopy. In scanning optical microscopy, however, the serial fashion of image acquisition seems to challenge a direct implementation of traditional holography. Here we introduce synthetic optical holography (SOH) for quantitative(More)
We demonstrate quantitative phase mapping in confocal optical microscopy by applying synthetic optical holography (SOH), a recently introduced method for technically simple and fast phase imaging in scanning optical microscopy. SOH is implemented in a confocal microscope by simply adding a linearly moving reference mirror to the microscope setup, which(More)
Synthetic optical holography (SOH) provides efficient encoding of the complex optical signal, both amplitude and phase, for scanning imaging methods. Prior demonstrations have synthesized reference fields with a plane-wave-like linear variation of the phase with position. To record large images without probe-mirror synchronization, a long-travel,(More)
Optical activity and circular dichroism are fascinating physical phenomena originating from the interaction of light with chiral molecules or other nano objects lacking mirror symmetries in three-dimensional (3D) space. While chiral optical properties are weak in most of naturally occurring materials, they can be engineered and significantly enhanced in(More)
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