Martin Schmollinger

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ii Acknowledgments First, I thank the Lord Jesus Christ for seeing me through my Ph.D work in Computational Biology. I looked back and remembered when I arrived in Tübingen end of March, 1998 during a prolonged winter period to begin my Ph.D work at the beginning of April, 1998. Exactly four year afters, I actually wrote the last character, which is a full(More)
BACKGROUND Parallel computing is frequently used to speed up computationally expensive tasks in Bioinformatics. RESULTS Herein, a parallel version of the multi-alignment program DIALIGN is introduced. We propose two ways of dividing the program into independent sub-routines that can be run on different processors: (a) pair-wise sequence alignments that(More)
SUMMARY Searches for variable motifs such as protein-binding sites or promoter regions are more complex than the search for casual motifs. For example, in amino acid sequences comparing motifs alone mostly proves to be insufficient to detect regions that represent proteins with a special function, because the function depends on biochemical properties of(More)