Learn More
We present experimental results and modeling on the efficacy of dielectrophoresis-based single-particle traps. Dielectrophoretic forces, caused by the interaction of nonuniform electric fields with objects, have been used to make planar quadrupole traps that can trap single beads. A simple experimental protocol was then used to measure how well the traps(More)
MOTIVATION Next-generation sequencing presents several statistical challenges, with one of the most fundamental being determining an individual's genotype from multiple aligned short read sequences at a position. Some simple approaches for genotype calling apply fixed filters, such as calling a heterozygote if more than a specified percentage of the reads(More)
Microfabrication uses integrated-circuit manufacturing technology supplemented by its own processes to create objects with dimensions in the range of micrometers to millimeters. These objects can have miniature moving parts, stationary structures, or both. Microfabrication has been used for many applications in biology and medicine. These applications fall(More)
Coinductive definitions, such as that of an infinite stream, may often be described by elegant logic programs, but ones for which SLD-refutation is of no value as SLD-derivations fall into infinite loops. Such definitions give rise to questions of lazy corecursive derivations and parallelism, as execution of such logic programs can have both recursive and(More)
We present the design and experimental analysis of a dielectrophoretic trap composed of four microfabricated gold posts excited in a quadrupolar fashion. Using quantitative modeling tools, we have designed these extruded traps to attain strong holding against flow while being constrained by a set of system parameters. The extruded geometry consists of(More)
The inner ears of 5 different gerbil species are compared on the basis of cochlear microphonic recordings, serial sections and computerized quantitative reconstructions of the cochleae and their specific morphological structures. The hearing range of most gerbils is below 20 kHz. Some species are extremely sensitive in the frequency range of 1-4 kHz. This(More)
Idiopathic dilated cardiomyopathy is generally considered a sporadic, nongenetic disorder, and reports of familial cases are often regarded as rare occurrences. Results of the present investigation of 6 families with this disorder suggest that familial forms of dilated cardiomyopathy occur more frequently than previously suspected. The familial nature of(More)